Creative Biolabs Announced the Preparation Technology and Clinical Application of Minibody

Oct 23, 2018, Creative Biolabs, a world-leading supplier and manufacturer in the field of recombinant antibody production, announced the preparation technology and clinical application of minibody, a novel engineered anti-carcinoembryonic antigen antibody fragment (Single-Chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts.

It is well-known that the minibody is an antibody fragment that has biological activity. Minibody, being consistent with a pair of single-chain Fv fragments. The common small molecule antibodies mainly include Fab (from the complete light chain and Fd structure). Fv (consisting of VH and VL), ScFv (single-chain antibody, VH and VL linked by a linked peptide), single-domain antibody (consisting of VH only), minimum recognition unit (MRU, consisting of a CDR), and hypervariable region polypeptide, double-chain antibody, triple-chain antibody, micro-antibody And so on. At present, single chain antibody, Fab antibody, single domain antibody and bispecific antibody are widely studied.

?At present, in Creative Biolabs, the expression system commonly used to produce minibody fragments is usually large. Enterobacter coli (E. coli) expression system, yeast expression system, insect cell expression system and mammalian cell expression system. The cost of expression increases in turn, but the accuracy and accuracy of post-translational processing decrease in turn. Because the primary structure, physical and chemical properties and biological activity of different small molecule antibodies are different, the selection of expression system should be based on the type, nature, expression and purity of the target products.? said Dr. Peterson, senior scientist in R&D of Creative Biolabs. ?In order to serve customers well, Creative Biolabs applies the most advanced platforms and technologies to guarantee the minibody and preparation technology with high quality.?

?With the development of bioengineering technology, the preparation of minibody is becoming more and more important. Easy, and the characteristics of minibody determine that they will have great potential applications in many fields of medicine, mainly in disease diagnosis, cancer. The application of sexual disease treatment and anti infection.? said the assistant of Dr. Peterson. ?So it is a chance and duty for Creative Biolabs to develop the high quality minibody antibody. And it will be sure that this product is going to be more and more popular.?

More detailed information about minibody can be found on its website.

About Creative Biolabs
Over ten-year experience in producing antibody, Creative Biolabs is very professional both in the production and application theory. What?s more, enjoying a good fame among antibody manufacturer, Creative Biolabs will be try its best to produce more practical antibody production.

Company :-Creative Biolabs

User :- Bella Smith

Email :-biolabs-marketing@outlook.com

Phone :---

Mobile:- -