Long Range Genomic Sequencing Article Reveals DNA Fragment Generation Tip

BitesizeBio.com has published a new article entitled "Extract HMW DNA for Long-Range Genomic Analysis with the New SageHLS Platform", which sheds light on the most important aspects of extracting high molecular weight DNA for sequencing. Bitesize Bio targets those working in Life Sciences and those interested in developments in the field. The full article can be read on the [BitesizeBio website](http://bitesizebio.com/product_article/extract-hmw-dna-long-range-genomic-analysis-new-sagehls-platform).

The article includes several interesting pieces of information, one in particular is that you can generate fragments as long as 2 Mb using the Sage HLS platform. This should be of particular interest to bioscientists because generating high molecular weight DNA fragments for sequencing is difficult, and 2 Mb is outside of most labs capabilities.

One of the most important piece of information the article conveys is that dealing with high molecular weight DNA for long range sequencing does not have to be difficult. The best example of this is perhaps found in the following extract:

'Thats why Sage Science has released the new SageHLS platform. This automated sample prep device produces ultra-long DNA fragments to enable long-range genomic analysis. The SageHLS instrument relies on electrophoresis to isolate DNA from cells, generating fragments as long as 2 Mb. It can also be used with Cas9 and guide RNAs to purify whole genes of interest.'

In discussing the article's creation, Dr. Amanda Welch, Editorial Manager of BitesizeBio.com said, "This platform will remove barriers that laboratories may have regarding investigating structural variants of DNA regions. We hope that this will help our readers further their research goals.

Regular readers of BitesizeBio.com will notice the article takes a familiar tone. The website has been described as 'the Missing Manual for Bioscientists', and started in 2007 as a personal blog. It has since grown to be one of the most loved of science websites, with hundreds of thousands of visitors every month.

This specific article has been produced with help from [Sage Science](http://www.sagescience.com/). Sage Science develops sample prep technologies for life science research. They focus on electrophoretic approaches that improve and automate high-value steps in Next Gen sequencing workflows.

Keeping up with the latest Bitesize Bio articles can be done by visiting their [Facebook page](https://www.facebook.com/BitesizeBiocom-119998064679182/).

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